Poor Benefit/Risk Balance of Intravenous Immunoglobulins in DRESS

Intravenous immunoglobulins control scleromyxoedema.

BACKGROUND Scleromyxoedema is a variant of papular mucinosis affecting the skin and internal organs. The different therapeutic approaches proposed for scleromyxoedema are still unsatisfactory. Intravenous immunoglobulin (IVIg) has been successfully employed in the treatment of connective tissue diseases and vasculitides. PATIENTS The successful treatment of three cases of scleromyxoedema with...

Intravenous Immunoglobulins in the Therapy Of

Intravenous immunoglobulin (IVIG) is used for the treatment of numerous immunodeficiency, immune-mediated, and inflammatory disorders in humans. More recently, it has been described for the therapy of immune-mediated hematologic disease in dogs. While the potential benefits of IVIG are tantalizing, and initial reports in dogs are encouraging, there is a marked paucity of controlled studies in t...

Autoimmune neuropathies and treatment with intravenous immunoglobulins

The therapeutic uses of intravenous immunoglobulins in autoimmune rheumatic diseases.

Immunoglobulins (antibodies) are plasma proteins produced by B cells, which are essential in the defence against bacterial and viral infections. Dysregulation of the immune system can lead to the formation of autoantibodies and subsequent autoimmune disease. Therapy with immunoglobulin was first studied in the late 19th century, when Von Behring and Kitasato showed that serum taken from rabbits...

Clinical utility of intravenous immunoglobulins in autoimmune diseases

Durante los últimos años, la utilización de las inmunoglobulinas endovenosas (Ig ev) se ha extendido desde las inmunodeficiencias primarias, a una serie de entidades clínicas como los procesos infecciosos, las enfermedades neurológicas inflamatorias y las enfermedades autoinmunes. Las Ig ev son una terapia bien tolerada, con pocos efectos adversos, aunque con un elevado coste económico. Aunque ...